The below article from explains how a new electropulse therapy may be producing holes in actual tumors resulting in the death of the cancerous tumor cells.   The process, IRE - Irreversible electroporation operates on a principle of opening the cancer cell membrane by using higher intensity and greater pulse width duration of the electrical charge which results in keeping open molecules, inside the cancer cells, and death results.   The process is invasive and the application electrode is inserted inside the body.  

   According to the work of Dr. Albert Szent-Gyorgi, Nobel Prize Medicine 1937 for Szent-Gyorgi/Krebs Citric Acid Cycle, any "opening" from a submolecular level is the supplementing of excess electrons into the molecules, which are collections of atoms with stable and unstable electron rings around the nucleus.   The flow or feeding of electrons disrupts cycles of growth, especially in cancer cells which are growing unnaturally and rapidly.   The growth process of the cancer cells exposes them to the constant rearrangment of electrons in the shells surrounding the nucleus and this may be what is atomically known as "keeping open the molecule".  Because many healthy tissues in the body are not in some super growth state the effects are only on rapid growth cells, not healthy normal cells. 

   The below article is a new technique intended to be used in high risk areas where cancer resides and other therapies pose additional risk to the patient with conventional treatments.   The use of high frequency interferential type currents do  decrease external resistances which should result in the lack of need for physical surgery and internal intervention.  By decreasing resistances the current can now be directed to the actual targeted cancer cells.  More work needs to be done in this area but with the introduction of the Infrex FRM we feel the instrument is here that can target the cancer cells. 



Cancer treatment that PUNCHES HOLES in tumours could be latest weapon in war against disease

  • New treatment uses millions of electric pulses per second to make holes in cancer cells and kill them
  • Therapy does not damage surrounding healthy tissue
  • Now experts want to carry out larger clinical trials 


A minimally invasive cancer treatment that punches microscopic holes in tumours - without harming surrounding healthy tissue - could be the latest weapon in the war against cancer.

Irreversible electroporation (IRE) uses millions of electrical pulses per second to kill cancer cells but spare nearby tissue.

‘IRE may be especially beneficial in treating liver, lung, pancreatic and other cancers that are close to blood vessels, nerves and other sensitive structures,’ said the researchers who conducted the study.

New hope: IRE uses electric pulses to kills tumours at a cellular level

New hope: IRE uses electric pulses to kills tumours at a cellular level


  Treatment of cancers near sensitive sites usually involves surgery and a technique known as thermoablation, which heats and then freezes the tumour. 

But this can damage healthy tissue, posing a risk to nearby major blood vessels, nerves, ducts and other vital structures.

The study involved 25 patients who suffered with cancer that had spread to various parts of their body. The average size of the tumour was two centimeters.




IRE was used due to the location of the lesions – all were near vulnerable sites that would be affected by thermoablation. 

Dr Constantinos Sofocleous, an interventional radiologist at Memorial Sloan-Kettering Cancer Center in New York, completed all 30 treatment sessions with no major complications, showing IRE to be safe enough for further investigation in larger clinical trials. 

Until now, the main method of removing tumours that had spread was by surgery and thermoablation

Until now, the main method of removing tumours that had spread was by surgery and thermoablation

He presented his findings at the Society of Interventional Radiology's 38th Annual Scientific Meeting in New Orleans. 

He said: ‘The treatment appears to be especially beneficial in people with cancer that has spread and who do not have good treatment options.'

IRE involves making an incision the size of a pencil tip and feeding a tiny instrument to target the tumours. 

Strong electric fields are then generated to create tiny holes in the cancer cell membranes.

This kills them by disrupting the balance of molecules inside and outside the cell. 

Because IRE does not generate heat or cold, it stops surrounding cells becoming damaged. 

This makes IRE ideal for treating tumors close to tissues that are vulnerable to damage.

By increasing the strength, and duration of the electric pulses, the pores in the cancer cells remain open permanently. 

This causes microscopic damage to the cells, and they die.

The combination of minimally invasive surgery and IRE allows for faster recovery with less tissue injury, and it is hoped, a better long-term outcome than with traditional surgery. 

At a minimum, said Dr Sofocleous, the treatment offers the the patient an improved quality of life.

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